Herpes hiv vaccine : Two Harvard Medical School researchers working toward an HIV vaccine are yielding promising results using a novel viral vector known for its longevity, according to a study in the September Journal of Virology.
David Knipe, professor of microbiology and molecular genetics and a specialist in herpes simplex virus, and HIV vaccine researcher Ronald Desrosiers, professor of microbiology and molecular genetics and director of the New England Regional Primate Research Center, have developed a live attenuated vaccine from a modified form of the herpes simplex virus that transports into host cells and expresses proteins from the simian immunodeficiency virus, or SIV, the non-human equivalent of HIV. Knipe and Desrosiers hope that a herpesvirus transport -- or vector -- of SIV fragments and potentially HIV fragments will provide a key difference that other vaccine vectors have lacked: like a bad guest, it simply refuses to leave.
Read more : http://www.sciencedaily.com/releases/2000/09/000904093112.htm